The Advanced Response Complex Face | Neck Cream

Highlights

Suitable for

All skin types, especially mature, sensitive, aging, and acne-prone.

Why we stand behind it

Plant-Growth FactorsTGFβ2, derived from Nicotiana benthamiana, anchors the formula. These naturally occurring growth factor proteins help support the appearance of firmer, more resilient skin as the skin’s own growth factor activity declines with age. Three distinct peptide complexes round out the formula, addressing multiple visible aging pathways at once.

A defining feature is a patented active composed of Australian Paw Paw Extract and organic kangaroo paw flower (Anigozanthos flavidus). Its mechanism is structural: it helps support the synthesis of Tenascin-X, a glycoprotein essential to organizing the extracellular matrix, where collagen fibrils and elastin fibers are arranged to support firmness and resilience. Where most anti-aging actives focus on collagen or elastin alone, Tenascin-X helps govern the relationship between them — supporting the integrity of the skin’s underlying framework. The active also helps support collagen and elastin synthesis and fibroblast activity.

Chebula and Astaxanthin deliver antioxidant support, helping neutralize oxidative stress while promoting a brighter, more even-looking complexion. The formula is also exceptionally concentrated — just 38% water versus the industry norm of approximately 90% — leaving meaningfully more room for performance-driven actives. It is housed in a PCR jar with a refill option.

Key ingredients

plant-TGFβ2 (Nicotiana Benthamiana-derived: At 2%, maximum concentration for skincare; helps support the appearance of firmer skin

Multiple Peptide Complexes: Support the look of firmer, more resilient skin via distinct pathways

(Australian Paw Paw Extract / Anigozanthos Flavidus): Increases Tenascin-X synthesis; regulates collagen fibril + elastin fiber architecture; supports the look of firmer, more resilient skin

Aloe Barbadensis Leaf (Aloe) Juice*, Orbignya Oleifera (Babassu) Oil*, Butyrospermum Parkii (Shea) Butter, Isoamyl Laurate, Isoamyl Cocoate, Cetearyl Alcohol, Coco-Glucoside, Salvia Hispanica (Chia) Seed Oil (and) Haematococcus Pluvialis Algal (Astaxanthin) Extract, Simmondsia Chinensis (Jojoba) Seed Oil*, Caprylic/Capric Triglyceride, Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-76, Hexapeptide-11, Tripeptide-29, Terminalia Chebula Fruit Extract, Camellia Sinensis Leaf (Green Tea) Extract, Anigozanthos Favidus (Australian Paw Paw) Extract*, Xylitylglucoside, Anhydroxylitol, Xylitol, Saccharide Isomerate, Lupinus Albus Seed Extract, Helianthus Annuus (Sunflower) Seed Oil, Glycerin, Lactobacillus/Dipteryx Odorata Seed Ferment Filtrate, Sodium PCA , Carthamus Tinctorius (Safflower) Seed Oil, Spilanthes Acmella Flower/Leaf/Stem Extract, Astragalus Membranaceus Root Extract, Sodium Lactate, Vegetable Oil, Arginine, Aspartic Acid, Glycine, Alanine, Serine, Valine, Proline, Threonine, Isoleucine, Histidine, Phenylalanine, Saccharomyces/Zinc Ferment, Saccharomyces/Copper Ferment, Saccharomyces/Magnesium Ferment, Saccharomyces/Iron Ferment, Saccharomyces/Silicon Ferment, Dipalmitoyl Hydroxyproline, Polyglyceryl-3 Beeswax, Asiaticoside, Madecassic Acid, Asiatic Acid, Hyaluronic Acid, Ubiquinone, Tocopherol, Acacia Senegal Gum, Xanthan Gum, Boswellia Carterii, Sodium Phytate, Benzyl Alcohol, Salicylic Acid, Glycerin, Sorbic Acid, Citric Acid, Sodium Citrate.*Certified Organic